A 30 year old female presents with muscle weakness and fatigue. Abnormal electromyography testing and a positive increase in ACTH receptor test is reported. Her final diagnosis is Myasthenia Gravis.
Describe the normal synaptic transmission at the Neuromuscular Junction (NMJ).
Why is the ACTH level increased?
Explain why the patient with myasthenia gravis cannot generate consistent action potentials in the muscle fiber.
Treatment for the patient involves pyridostigmine—what does this drug do and how would it benefit our patient?
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